• Question: Why isn't there a cure for MND?

    Asked by Megan <3 to Siana, Sara, Richard, Peter, Carolyn on 17 Nov 2015.
    • Photo: Richard Unwin

      Richard Unwin answered on 17 Nov 2015:


      Motor neurone disease is a very complicated disease which occurs in the brain and specifically affect ‘motor neurones’, the nerves that control our movements. We know some of the things that happen in MND but don’t understand them fully so it’s hard to make new medicines. However at least two medicines are being tested at the moment. One is a medicine which blocks a protein called NOGO-A, which is found at higher levels in people with MND and stops nerves growing properly (the hope being that by blocking the NOGO the nerves will begin to grow and function normall again. the second is a clever method where cells are taken from the bone marrow, are turned into nerve cells in the lab, then reinjected to replace the nerves that have died.
      So research IS ongoing, but it’s a very hard and complicated disease to understand – there’s a whole science career in MND research waiting, if you want it!

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